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Purine-Rich Element Binding Protein A (PURA) (N-Term) Peptide

PURA Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN982478

Aperçu rapide pour Purine-Rich Element Binding Protein A (PURA) (N-Term) Peptide (ABIN982478)

Antigène

PURA (Purine-Rich Element Binding Protein A (PURA))

Origine

Humain

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-PURA antibody (Catalog #: ARP38688_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    PURA (Purine-Rich Element Binding Protein A (PURA))

    Sujet

    PURA is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: PUR-ALPHA, PUR1, PURALPHA

    Protein Interaction Partner: Jvgp5,YBX1,ADAP1,CCNT1,CDK5,E2F1,PURB,RB1,SP1,YBX1,CCNT1,CNBP,E2F1,HNRNPA1,MEPCE,SP1

    Protein Size: 322

    Poids moléculaire

    35 kDa

    ID gène

    5813

    NCBI Accession

    NM_005859, NP_005850

    UniProt

    Q00577
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